Honestly there aren’t a whole lot of DC books that I read for pure comedy. I feel like, at least in recent years, DC has aimed squarely at the “dead serious” target. Unlike a lot of people, I’m not a huge fan of Conner/Palmiotti Harley Quinn. I respect their take and their commitment to the series (like 70+ issues, including miniseries and the start of the Rebirth book; that’s dedication!), although I don’t really like it or find it particularly funny. A lot of the older books that people recommend as comedic I also don’t find very funny. Humor is often a product of its time. Ambush Bug doesn’t do a lot for me. JLI is great, and it is funny, but it also isn’t a pure comedy. It’s got a lot of serious dramatic elements that don’t make it the ideal funny book to give to someone who needs a laugh.
So, what are the funniest comics? Most of the stuff Mark Russell’s been doing over the past handful of years has been amazing. The recently-finished Wonder Twins might actually be his best work. Although Flintstones, Snagglepuss, and Prez are all excellent as well. It’s sharp satire mixed with creativity and wonderful timing. All of which are hard to do in comics. Also of note is the current, sadly almost finished Jimmy Olsen series. Steve Lieber’s art accentuates Matt Fraction’s comedic stylings to new heights. It’s amazing.
Those are really it as far as I can think of in way of DC. I’m sure there are others that people can come up with. Overall, though, I think Marvel’s been beating DC at the funny game for a while now. The Superior Foes of Spider-Man is hysterical. Nextwave is a stone-cold classic. Welcome Back Frank (while hard to read now through no fault of its own) is a genius dark comedy. The (somewhat) recent Power Man and Iron Fist series by David Walker and Sanford Greene is amazing.
Point being, I’d really like to see DC focus more heavily on humor. They’re doing good at it, but I’d like to see them do even better.