In the fifties, there was a story in Black Magic from Prize Comics (Vol. 1, 30) drawn by Kirby called Head of the Family. (Prize was bought by DC and they republished that story in the 70’s.) It involved quadruplets that are psychically linked. The “head of the family” has a big head and small body and controls the other three. Two of the siblings include one strong guy and one with excellent senses.
Though the general story and names are different, Full Moon/Charles Band’s movie of the same also has quadruplets controlled by the brother with a large head and small body. There is a strong guy and one with excellent senses.
Seems like more than a coincidence.