I finished season 2 the other day. George Reeves is just excellent as both Clark Kent and Superman. Noel Neil takes over as Lois Lane for Phyllis Coates. There are 3 episodes from this season that were my favorites.
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The Defeat Of Superman introduces Kryptonite for the first time on the show.
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Superman In Exile features Superman stopping an atomic disaster. He becomes radio active and has to retreat away from civilization.
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Panic In The Sky features Superman attempting to stop an asteroid coming to Earth. He fails to completely stop the asteroid, and he gets amnesia from the impact.